How are visual responses modulated by stimulus context in time (adaptation) and space (surround modulation)? How do contextual effects at early visual processing levels influence processing at higher levels? How do the effects of spatiotemporal context on visual processing vary between early and late cortical processing stages? How are contextual effects measured by BOLD related to underlying neuronal responses? How do top-down effect modulate contextual effects?
Contextual modulation effects are ubiquitous in neuronal processing, but relatively little is known about how these effects manifest in BOLD fMRI responses and how this technique can be used to study these phenomena. In this project funded by Wellcome Trust we use a combination of fMRI and psychophysics to investigate these questions.